Disease Modeling Core
The Disease Modeling Core (DM Core) is dedicated to advancing the understanding of urological diseases by developing and utilizing advanced disease models. Our work spans benign urological disorders, transplantation, and oncology, providing critical insights into disease mechanisms, identifying therapeutic targets, and testing novel treatments.
What We Do
Understanding Urological Diseases – We study disease initiation and progression to uncover new treatment strategies.
Model Development – Using over 30 years of expertise, we establish in vitro and in vivo models that replicate human urological diseases, including patient-derived xenografts, genetically modified cancer models, urinary tract infection and stone formation models, and 3D bioprinting of urologic organs.
Therapeutic Testing – We evaluate novel drugs and technologies, supporting rapid translation from research to clinical application.
Technology & Expertise
DM Core is supported by a team of experts specializing in urological disease modeling, imaging, and therapeutics. We utilize state-of-the-art technologies to initiate disease processes, introduce test compounds with precision, track disease progression, and assess treatment outcomes.
Collaboration & Integration
As an integral part of the Institute of Urology, DM Core collaborates with researchers, clinicians, and industry partners to drive innovation in urological disease research and treatment development.