Mr. Jonathan Ma
Prostate Clinic/Department of Urology, VGH
Clinical Trials Core
The M.H. Mohseni Urology Institute of Urological Sciences, in collaboration with BC Cancer, leverages national and international networks to conduct comprehensive clinical trials, focusing on enhancing patient enrollment and ensuring thorough follow-up through Canada’s centralized medical system. By integrating genitourinary research programs, the institute offers patients access to a diverse range of investigational studies. The team has extensive experience in cooperative and industry-sponsored trials with leading pharmaceutical and biotech companies, successfully submitting trials to Health Canada and meeting regulatory standards audited by Health Canada and the US FDA.
Overview
Clinical trials are a core component of the M.H. Mohseni Urology Institute of Urological Sciences (MUIS), conducted through its dedicated clinical trials unit located within the Vancouver Prostate Centre and in close collaboration with BC Cancer. These trials span a broad range of urological conditions, including both oncological and non-oncological diseases such as prostate and bladder cancers, and kidney stones.
Our clinical research efforts are integrated with national and international clinical trial networks and industry partners, which enhances patient enrollment and access to cutting-edge investigational therapies. The centralized structure of the Canadian healthcare system and coordinated treatment centers like MUIS allow for comprehensive and consistent patient follow-up and data collection.
By combining the genitourinary research programs at MUIS and BC Cancer, patients can access a robust portfolio of cooperative group and industry-sponsored trials, including studies supported by major pharmaceutical and biotech companies. The Institute has submitted trials to Health Canada and has successfully undergone audits by both Health Canada and the U.S. Food and Drug Administration (FDA), demonstrating our commitment to high regulatory and ethical standards.
To view a list of currently active trials, please visit Trials Open to Enrollment
Expertise
The Clinical Trials Service at the M.H. Mohseni Urology Institute of Urological Sciences builds on more than 20 years of experience in conducting superior quality clinical trials in a variety of indications. Our highly-qualified team of investigators and support staff include:
- Four full-time urologists
- Three full-time medical oncologists
- Nine full-time clinical trial coordinators
- Six registered nurses
- Three regulatory affairs assistants
- Administrative support staff
Services
Our core services include:
- Coordination of Phase I though III Clinical Trials
- Pharmacokinetic, pharmacodynamic and biomarker studies
- Proof of concept trials
- Standardized protocols for adjuvant drug studies prior to radical prostatectomy (allowing tissue analysis following drug exposure)
- Safety/efficacy studies with single agent or combination therapies
- Long term surveillance studies
- QOL and outcome studies
- Development of clinical trial protocols
- Preparation of regulatory and ethical documentation for submission to health Canada and Institutional Review Boards (IRBs)
- Negotiation of Clinical Trial Agreements and Budgets
- Development of study specific SOPs
- Collection, entry, processing and analysis of clinical trials data and patient derived samples
- Experience with both paper and electronic CRFs
- Preparation of clinical study reports
- Access to national and international multi-centre networks for GU tumor clinical trials